Published Works

Publications:

Säfholm,. S-E. Dahlén, I. Delin, K. Maxey, K. Stark, L-O. Cardell, M. Adner, “Prostaglandin E2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors.” British Journal of Pharmacology (2013) 168:794-806.                                                                                                              Download the PDF.

K.M. Maxey, J.L. Johnson, J. LaBrecque, “The Hydrolysis of Bimatoprost in Corneal Tissue Generates a Potent Prostanoid FP Receptor Agonist.” Survey of Ophthalmology (2002) 47(Supplement 1):S34-S40. Download the PDF.

K.M. Maxey, E. Hessler, J. MacDonald, L. Hitchingham, “The Nature and Composition of 15-deoxy-D12,14PGJ2.” Prostglandins & other Lipid Mediators (2000) 62:15-21.       Download the PDF.

Kim S, Powell WS, Lawson JA, Jacobo SH, Pratico D, FitzGerald GA, Maxey K, Rokach J., “iPF2alpha-III-17,18,19,20-d4: total synthesis and metabolism” Bioorganic & Medicinal Chemistry Letters (2005) 15:1613-7. Download the PDF.

Kim S, Bellone S, Maxey KM, Powell WS, Lee GJ, Rokach J., “Synthesis of 15R-PGD2: a potential DP2 receptor agonist” Bioorganic & Medicinal Chemistry Letters (2005) 15:1873-6. Download the PDF.

J.Y. Westcott, K.M. Maxey, J. MacDonald, S.E. Wenzel, “Immunoaffinity Resin for Purification of Urinary Leukotriene E4.” Prostglandins & other Lipid Mediators (1998) 55:301-321. Download the PDF.

Brooks, L.W. Byers, E.E. Muirhead, M. Muirhead, J.A. Pitcock, K.R. Maddipati, K.M. Maxey, “Purification of Class I Medullipins from the Venous Effluent of Isolated Normal Kidneys Perfused under High Pressure with Saline.” Blood Pressure (1994) 3:407-417.          Download the Abstract.

K.M. Maxey, K-R. Maddipati, J. Birkmeier, “Interference in Enzyme Immunoassays.” Journal of Clinical Immunoassay. (1992) 15:116-120. Download the PDF.

R.P. Del Vecchio, K.M. Maxey, G.S. Lewis, “A Quantitative Solid-Phase Enzyme immunoassay for 13,14-Dihydro-15-keto-Prostaglandin F2a in Plasma.” Prostaglandins (1992) 43:321-330. Download the PDF.

R.R. Gorman, K.M. Maxey, G.L. Bundy, “Inhibition of Human Platelet Thromboxane Synthetase by 11a-Carbathromboxane A2 Analogs.” Biochemical and Biophysical Research Communications. (1981) 100:184-190. Download the PDF.

K.M. Maxey, G.L. Bundy, “The Synthesis of 11a-Carbathromboxane A2.” Tetrahedron Letters. (1980) 21:445-448. Download the PDF.

G.L. Bundy, F.A. Kimball, A. Robert, J.W. Aiken, K.M. Maxey, O.K. Sebek, N.A. Nelson, J.C. Sih, W.L. Miller, R.S.P. Hsi, “Synthesis and Biological Activity of 9-Deoxo-9-Methylene and Related Prostaglandins.” Advances in Prostaglandin and Thromboxane Research. (1980) 6:355-363. Download the PDF. 

 

Patents and Applications:

Tetranor-prostaglandin E2 metabolite and tetranor-prostaglandin A2 metabolite -specific immunogens, antibodies, tracers, and assay kits                                    Download the PDF.

Patent applications filed for this family (no patents issued or granted yet):

  1. United States Patent Application No. US 2011/0311990 filed June 14, 2011   Published: December 22, 2011                                                                                   Inventors: Kirk M. Maxey, Jeffrey K. Johnson, Andriy M. Kornilov, Daniel J. Tew
  1. PCT Application No. WO 2011/159741 filed June 14, 2011                                        Published: December 22, 2011                                                                                       Inventors: Kirk M. Maxey, Jeffrey K. Johnson, Andriy M. Kornilov, Daniel J. Tew

Tetranor-prostaglandin D2 metabolite and tetranor-prostaglandin J2 metabolite -specific immunogens, antibodies, tracers, and assay kits                                    Download the PDF.

Patent applications filed for this family (no patents issued or granted yet):

  1. United States Patent Application No. US 2012/0021437 filed June 14, 2011                Published: January 26, 2012                                                                                              Inventors: Kirk M. Maxey, Jeffrey K. Johnson, Andriy M. Kornilov, Daniel J. Tew
  2. PCT Application No. WO 2011/159735 filed June 14, 2011                                          Published: December 22, 2011                                                                                  Inventors: Kirk M. Maxey, Jeffrey K. Johnson, Andriy M. Kornilov, Daniel J. Tew

Method for assaying compounds or agents for ability to displace potent ligands of hematopoietic prostaglandin D Synthase                                                                            Download the PDF.

Issued patent from patent family originating with United States patent application publication U.S. 2009/0286261 filed on November 19 2009.

  1. United States Patent 8,440,417 issued May 14, 2013; Inventors: Nisha Palackal, Jeffrey K. Johnson, Karie L. McGowan, Kirk M. Maxey, Gregory W. Endres
  1. Australia Patent AU 2009246446 issued June 26, 2014; Inventors: Nisha Palackal, Jeffrey K. Johnson, Karie L. McGowan, Kirk M. Maxey, Gregory W. Endres
  2. Israel Patent IL 208850 issued November 21, 2014; Inventors: Nisha Palackal, Jeffrey K. Johnson, Karie L. McGowan, Kirk M. Maxey, Gregory W. Endres

 

Prostaglandin E1 and E2 analogs for the treatment of various medical conditions     Download the PDF.

Issued patent from patent family originating with United States patent application publications US 2009/0124695 and US 2009/0221654, and PCT publications WO 2009/065070 and WO 2009/065081, all filed on November 14, 2008:

United States Patent 8,063,240 issued on November 22, 2011; Inventors: Kirk M. Maxey, Nancy S. Barta, Stephen D. Barrett, Gregory W. Endres, Andriy M. Kornilov, Adam Uzieblo

 

Method for screening of prostaglandin compounds comprising an optimal formulation for the enhancement of hair growth and the stimulation of follicular anagen and formulations resulting therefrom                                                         Download the PDF.

Patent applications filed for this family (no patents issued or granted):

  1. United States Patent Application No. US 2009/0088473 filed September 26, 2008           Published: April 2, 2009                                                                                                         Inventor: Kirk M. Maxey
  1. PCT Application No. WO 2009/045908 filed September 26, 2008                     Published: April 9, 2009                                                                                                          Inventor: Kirk M. Maxey

 

Methods and kits for detection of thromboxane A2 metabolites                             Download the PDF.

Issued patents from patent family originating with United States patent application publication US 2007/0202556 filed on December 11, 2006:

  1. United States Patent 7,727,730 issued June 1, 2010; Inventors: Kirk M. Maxey, Jon F. Geske, Daniel Tew, Amy Whittier
  2. United States Patent 8,105,790 issued January 31, 2012; Inventors: Kirk M. Maxey, Jon F. Geske, Daniel Tew, Amy Whittier
  3. United States Patent 8,168,400 issued May 1, 2012; Inventors: Kirk M. Maxey, Jon F. Geske, Daniel Tew, Amy Whittier

 

Prostaglandin F2α analogs in combination with antimicrobial proteins for the treatment of glaucoma                                                                                                          Download the PDF.

Granted patents from patent family originating with PCT publication WO 2003/079997, Australian patent application 2003/222049, European patent application EP 1501530, Japanese patent application 2005/5260924, and Austrian patent application 422894, all filed on March 21, 2003:

  1. Australian Patent AU 2003/222049 issued September 13, 2007; Inventors: Kirk M. Maxey, Jennifer Johnson
  2. European Patent EP 1501530 issued February 18, 2009; Inventors: Kirk M. Maxey, Jennifer Johnson
  3. Switzerland Patent CH

 

Systems and Methods for Providing Open Access to Scientific Information   Download the PDF.

PCT application filed for this family (no patents issued or granted – family abandoned): PCT Application No. WO 2007/024811 filed August 21, 2006                                      Published: March 1, 2007                                                                                                          Inventor: Kirk Michael Maxey

 

Preparation of macrocyclic 1,15-lactones of fluprostenol and related prostaglandin F2α analogs for use in the treatment of glaucoma and intraocular hypertension Download the PDF.

Issued and granted patents from patent family originating with United States patent application publication US 2001/0046982, PCT publication WO 2001/057015, Australian patent application 2001/233286, European patent application EP 1261598, and Japanese patent application 2003/531824, all filed on February 1, 2001:

  1. United States Patent 7,358,275 issued April 15, 2008; Inventors: Kirk M. Maxey, Michelle L. Stanton
  2. United States Patent 7,585,889 issued September 8, 2009; Inventors: Kirk M. Maxey, Michelle L. Stanton
  3. United States Patent 7,674,921 issued March 9, 2010; Inventors: Kirk M. Maxey, Michelle L. Stanton
  4. Australian Patent 2001/233286 granted July 20, 2006; Inventors: Kirk M. Maxey, Michelle L. Stanton

 

Isoprostane-protein conjugates for EIA                                                                             Download the PDF.

Patent applications filed for this family (no patents issued or granted):

  1. PCT Application No. WO 94/04921 filed August 11, 1993                                          Published: March 3, 1994                                                                                                    Inventors: Kirk M. Maxey, Waiming Kan
  1. Australian Application No. AU 93/50099 filed August 11, 1993                                      Published: March 15, 1994                                                                                                Inventors: Kirk M. Maxey, Waiming Kan

 

Organic Compounds Substituted Heptadeca-5,9- and 5,10-Dienoic Acid                  Download the PDF.

United States Patent 4,352,760 filed December 29, 1980                                                             Issued: October 5, 1982                                                                                                                  Inventor: Kirk M. Maxey